Effects of ozone exposure in rat lungs investigated with hyperpolarized3He MRI
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چکیده
منابع مشابه
Effects of glass fiber exposure on rat lungs.
As is generally known, asbestos is physico chemically and economically suitable for building materials. However, respirable fine fibers of as bestos have been confirmed to cause asbestosis, bronchial cancer and pleural and peritoneal meso thelioma. As alternatives of asbestos, man-made mineral fibers such as glass fibers, ceramic fibers and others have been developed, but how they affect a pers...
متن کاملEffects of Acute Intraperitoneal Injection on Plural Rat Lungs
Purpose: Sulfur mustard (SM), a highly toxic chemical warfare, primarily targets the skin, eye and respiratory tract. Respiratory tract lesions are the most disabling consequences. Mast cells, containing special granules that store histamine and heparin, release leukotrienes. It is known that the surface of mast cells contains specific receptors for 19B. Therefore, mast cells promote allergic r...
متن کاملThe Study of Histological Effects of Solder Fumes in Rat Lungs
Objective(s) To determine the potential toxic effects of manual soldering flux cored solder wire on lung of the rat as an experimental model. Materials and Methods A total number of 48 adult male rats were divided into experimental (n= 30) and control (n= 18) groups. Based on exposure time to solder fume, each group was further subdivided into 2, 4 and 6 week subgroups. Rats of experimental ...
متن کاملCo-Exposure Effects of LPS with Various Aflatoxin B1 Doses in Isolated Perfused Rat Liver Model
Background: Activation of inflammatory cells can cause more chemicals induced-hepatotoxicity. Aflatoxin B1 (AFB1) is a fungal toxin that induces acute hepatotoxicity in humans and animals. This study was conducted to examine the effect of co-exposure LPS and various aflatoxin B1 doses on the damage hepatic parameters in isolated perfused rat liver. Methods: Thirty-two male wistar rats (250-3...
متن کاملEffects of acute hyperoxic exposure on solute fluxes across the blood-gas barrier in rat lungs.
We investigated effects of acute hyperoxia on solute transport from air space to vascular space in isolated rat lungs. Air spaces were filled with Krebs-Ringer bicarbonate solution containing fluorescein isothiocyanate-labeled dextran (FD-20; mol wt 20,000) and either 22Na+ and [14C]sucrose, or D-[14C]glucose and L-[3H]glucose. Apparent permeability-surface area products for tracers over time (...
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ژورنال
عنوان ژورنال: Journal of Magnetic Resonance Imaging
سال: 2008
ISSN: 1053-1807,1522-2586
DOI: 10.1002/jmri.21216